stowers institute faculty

Halleh Balch is a physicist pioneering new technologies deployed on autonomous underwater vehicles (AUVs) to study oceanic microorganisms and their impact on climate and human health. Scientists know that psychiatric and autoimmune diseases, for example, have complicated genetic roots. SaraH Zanders, Ph.D., a geneticist, joined the Stowers Institute in 2016 and is an Associate Investigator. Martinez ultimately wants to understand how the immune mechanisms causing these reactions can be exploited to prevent or cure viral disease. Plants are essential for life on Earth. Some proteins form gels, some provide molecular transportation, and still others, such as spider silk, are stronger than steel by weight. Jasmin Camacho is studying wild bats using cutting-edge metabolomics to identify and map the metabolic mechanisms that protect against the damaging effects of sugar consumption. Stowers Institute for Medical Research 1 year 11 months Graduate Researcher Jun 2022 - Present1 year 2 months Research Scholar Sep 2021 - Jun 202210 months Kansas City, Missouri, United States. This detailed understanding of how cells stymie disease could lead to new strategies for treating infections. Biafra Ahanonu wants to understand the neural and molecular basis of pain, a complex experience that integrates sensory information with ongoing brain states. Neville Bethel wants to understand how microscopic molecules combine to take on such diverse roles. Mannheim University of Applied Sciences - Wikipedia Genetics and Genomics, Using advanced imaging and genetic techniques, hes untangling the mechanisms by which human cells activate proteins to block invaders. Carolyn Elya is studying how microbes hijack insect nervous systems. Molecular and Cell Biology, Cell Dynamics, Stem Cells and Developmental Biology; Laboratory Rotation; Thesis Laboratory. Alejandro Snchez Alvarado, Ph.D., is the President and Chief Scientific Officer of the Stowers Institute. Stowers Institute for Medical Research | News Ron Yu, Ph.D., is a molecular biologist and neuroscientist and an Investigator at the Stowers Institute since 2005. Cuentas-Condori will use the compact nervous system ofC. elegansto identify strategies that neurons use to organize different populations of synaptic vesicles along a single axon and how dual-transmitter signals integrate to modulate the behavior of a living animal. His interest in how organs develop prompted a focus on stem cells namely, their life span and maintenance. Through the International Society for Computational Biology, she has been one of the organizers of bioinfo-core, a group for people in bioinformatics core facilities to help share good ideas and get help and advice from others worldwide. Andrea Cuentas-Condoris research aims to understand how some neurons communicate using two different neurotransmitters rather than one. Bats are an extremely diverse and successful group of mammals. To address this long-standing problem of biology, Snchez Alvarado and his team use the planarian Schmidtea mediterraea as a model system. Unchecked inflammation is the hidden culprit behind many diseases including inflammatory bowel disease, rheumatoid arthritis, and Alzheimer's. The Stowers Institute for Medical Research is a non-profit, basic biomedical. By Ryan Stowers Higher ed's free speech controversies must be solved on campuses, not in the statehouse. Focusing on the nervous system inside the gut, often called the second brain, she is investigating the effects of gut microbiota and immune cells on the development and maintenance of gut neurons. Halfmann joined the Institute in 2015 as an Assistant Investigator. Drees received her medical degree from the University of Kansas and did her residency training in internal medicine and fellowship in endocrinology at the Kansas University Medical Center. Cox hopes that decoding those cellular signals will lead to novel ways of improving crop yields, and ultimately to feeding more people. She wants to probe the contents of these packets using mass spectrometry. Hamids studies of the interactions between dopamine-producing neurons and blood vessels could deepen our understanding of how blood hormones influence decision-making and goal-directed behavior. Hes reprogramming human skin cells in the lab to grow into brain immune cells called microglia. He continued his molecular studies in living cells during his postdoctoral studies in the Laboratory of Fluorescence Dynamics at the University of California, Irvine before joining the Stowers Institute as a research specialist in 2008. These molecules contain instructions for making proteins, which, in turn, guide cellular behavior. The 2021-2022 BioMedCAS application cycle is now closed. Molecular and Cell Biology, She is a professor in the Department of Internal Medicine and the Department of Biomedical and Health Informatics at the UMKC School of Medicine. Alejandro Snchez Alvarado is interested in the molecular and cellular mechanisms underpinning animal regeneration. Monika KORBMANN | Duale Hochschule Baden-Wrttemberg Karlsruhe Jerry Workman, Ph.D., an Investigator at the Stowers Institute, is known for his pioneering work uncovering the role of histones in the regulation of gene expression. Stowers Institute. Watch Video Stay tuned for the announcement of the 2024 competition. One family of immune proteins unravels molecular strings that some bacteria use to travel through infected cells. In this role, she oversees the external grants program at the Institute, beginning at the proposal stage through the award management stage. She is on the faculty at the University of Missouri-Kansas City (UMKC) School of Medicine where she is Dean Emerita after serving thirteen years as dean (2001-2014) and acting provost and vice chancellor for academic affairs (2007-2008). Coyote-Maestas looks for genetic mutations that change TrpV1s response to high temperatures, then uses high-resolution microscopes to examine how changes in temperature sensation alter protein structure. Linheng Li, Ph.D., joined the Stowers Institute in 2000 and focuses on stem cell and cancer research. Daniel Gonzales aims to eavesdrop on the chatter between brain cells. University students and faculty, institute members, and independent researchers. Back . Shan Meltzer is revealing how sensory neurons form the exquisite structures and connections that govern these cells functions. Madelaine Gogol is a Manager in the Computational Biology Core Facility at the Stowers Institute for Medical Research. Barnes also plans to uncover how the virus gains illicit entry into cells by examining the structural changes that help the virus lock into a cellular target. Focusing on a recently identified brain circuit that influences whether mice crave social interaction, Sullivan is studying how inflammation affects the neural circuits that shape social behavior in mice. She became the Computational Biology group leader in 2009 and Head of Computational Biology in 2017. Karlsruhe University of Applied Sciences - Wikipedia As a doctoral student, Quinodoz developed a new way to map how the nucleus is organized. Low levels of NAD+ have been linked to both aging and a wide range of diseases, including type-2 diabetes, Alzheimers, and cancer. After building microarray robots at the University of California, Berkeley, and Childrens Hospital of Oakland Research Institute, Seidel joined the Stowers Institute where he develops novel genomic approaches and analysis pipelines and continues to do research in genomics. His lab focuses on mammalian olfactory systems involved in perception and behavior. Learn more about how we move science forward. Dual-transmission is a conserved capacity of neuronal circuits that scientists are just starting to understand at the cellular and circuit levels. Stowers Institute for Medical Research | Careers Watch on Mallory already knows how to read patterns of brain activity to predict where the critter might be heading next. Faculty of Engineering. Balch hopes this work will uncover new catalysts, useful therapeutics, and pathways to greater climate resilience. Her work may lead to new ways to prevent disease progression and suggest novel strategies to control infection. Work closely with your care team or main doctor. Fisher is exploring the dynamic interactions between these channels in the fruit fly, by examining their activity in cells that may help the fly navigate using visual cues. One of the most important features of plant cells is the chloroplast, which originated from the capture of a cyanobacterium approximately a billion years ago and facilitates the process of photosynthesis. In her current role she oversees academic standards and predoctoral researcher support services in addition to serving as a member of the faculty and an academic advisor for predoctoral researchers. Kyle Card is using bacteria from various stages of the seminal E. coli long-term evolution experiment (LTEE) which has tracked bacterial evolution over more than 70,000 generations to examine how bacterias evolutionary history, together with population size and mutation rates, contribute to the evolution of antibiotic resistance and associated fitness costs. Faculty | Scripps Research Sick animals often withdraw socially, hiding instead of seeking affection. A trait that has evolved multiple times in bats is preference for a sugary nectar diet. Using retinal organoids retinal tissue cultures derived from human stem cells as a model system, Eldred seeks to understand the factors that help generate important cell types in the retina, as well as the factors that divert cells down an unplanned path toward tumorigenesis. The Graduate School of the Stowers Institute | Home Helena Raposo - Graduate Researcher - Stowers Institute for Medical However, many bacteria have developed resistance to these antibiotics. By studying craniosynostosis in zebrafish, he plans to uncover if and how stem cell depletion and dysfunction cause disease. Trainor joined the Institute in 2001, and is a leader in the fields of craniofacial, neural crest cell, and developmental biology. While these acids, known as hydroxycinnamic acids, are common in food, they accumulate at high levels in people with failing kidneys. Linking TrpV1s shape to its temperature sensitivity will help scientists better understand how we feel heat. U.S. Scholars U.S. Scholars. Nicolas Altemose is developing new technologies that use cutting-edge DNA sequencing machines to map protein-DNA interactions in uncharted regions of the human genome. Seidel grew up in the San Francisco Bay area and studied biochemistry and molecular biology at the University of California, Santa Cruz. Wint has extensive experience in program management, graduate career professional development, mentoring, and outreach. She received her Ph.D. in biochemistry and molecular biology from the University of Nebraska Medical Center, researching pancreatic cancer in the laboratory of Tony Hollingsworth, Ph.D. After completing postdoctoral research in the laboratory of Ting Xie, Ph.D., at the Stowers Institute, Lewallen transitioned into a role leading the strategic development of grant proposals for the Institute. Jose L. Alejo is investigating one of natures most important molecular machines, the ribosome. Alejandro Snchez Alvarado, PhD | HHMI Florentine Rutaganira wants to use chemical tools to decipher the roles of key signaling networks in choanoflagellates, single-celled organisms that are the closest living relatives of animals. Bonny is adapting and developing new tools to probe how cells communicate and coordinate the transition between inflammation and tissue repair. Graduate School at Stowers Institute granted accreditation Thiago Monteiro Arajo dos Santos finds the invisible world of microbes captivating. The results could clarify granules link to cancer, viral infection, and neurodegenerative disease. Alejos work could also shed light on the origin of life on Earth and how life might emerge elsewhere in the universe. The Graduate School was created by the scientists of the Stowers Institute for Medical Research to complement the mission of the Stowers Institute, "To make a significant contribution to. Denniss work will help scientists better translate findings across species. We can: Help you relieve pain and other symptoms, improving your quality of life. In tracking how such a wiring pattern emerges in developing fruit fly brains, Pual hopes to uncover insights about the organization of sensory perception more broadly. Using the genetic tool CRISPR to turn down the activity of specific genes and see what changes occur, Jinich hopes to identify and characterize hundreds of unknown enzymes, revealing new drug targets. Tessa Montague is investigating how these chameleons of the sea turn the background colors and patterns their eyes perceive into a matching display on their own skin. Kelsie Eichel is studying how neurons sort and dispatch proteins, and what happens when deliveries get lost along the way. Using widescale neural recordings and simultaneous physiological measurements, Bowen is mapping the neural networks and signaling underlying food value learning. Elya discovered and developed a model system for laboratory studies of this phenomenon using a fungus that infects fruit flies. RNA regulates gene expression by folding into complex structures and binding proteins. She then transitioned to a role as a Research Specialist in Microscopy, where she worked with laboratory researchers throughout the Stowers Institute to plan, perform, analyze and publish imaging experiments to address a wide range of biological questions. in biochemistry with a chemistry minor from Colorado State University. Parasites and their hosts shape one anothers evolution. She hopes her work will reveal how we learn to predict foods effect on the body and guide development of therapies for metabolic disease. By studying the byproducts produced when the acids are metabolized, Guthrie hopes to better understand their impact on the gut microbiome and their relationship to kidney disease. The Mannheim University of Applied Sciences is a public higher education institute located in Mannheim, Germany.Referred to as Hochschule Mannheim in German and previously known as Fachhochschule Mannheim, it offers degree programs at bachelor's and master's level in the fields of engineering, informatics, biotechnology, design, and social affairs. Edgar Medina studies chytrids, one of the most ancient lineages of fungi, to explore the evolutionary pressures and adaptations that spurred the divergence of fungi and animals. Ava Carter is working to understand how interpretation of sensory cues drives human brain development throughout childhood. A male fruit fly performs a rich courtship display to attract females of the same species. Scientists often rely on mice to probe neurodegenerative diseases. Michelle Hays is interested in how hosts evolve to fight back against parasites and the trade-offs associated with self-defense. She joined the Institute in 2002 and currently serves as an Investigator. Scott Hawley, Ph.D., joined the Stowers Institute in 2001, and is an Investigator for the Institute and Dean Emeritus for the Graduate School. Mammalian cells produce thousands of different RNA molecules that do not code for proteins, and their roles remain largely unexplored. Program Academics Foundational research is the essence of our program Designed to provide exceptionally talented researchers with the mentoring and hands-on experience required to prepare them for careers as independent scientists Genetics and Genomics, Willow Coyote-Maestas is detailing the mechanisms by which this protein senses heat. Molecular and Cell Biology, SN 10 Science News names SaraH in list of top ten scientists to watch in 2020. Need to meet with your instructor? Christopher Medinas research focuses on understanding the mechanisms of immune cell dysfunction at both a metabolic and protein level to help override this brake and reinvigorate the immune response. She is a member of Alpha Omega Alpha and Phi Kappa Phi honor societies, and is a Fellow in the American College of Physicians and the American College of Endocrinology. The work could provide insight into the origins and evolution of animal innate immunity, our first-line defense against microbial threats. John Brooks is investigating how mammals internal clocks affect microbes that live in the gut. Support your mental health and your emotional and spiritual needs. In response to stress, we adapt to avoid harm by enhancing the protective abilities and performance of key systems, including the auditory system, which must increase its sensitivity while also preventing itself from failing. His results could expose how the clock/microbiota interplay shapes the health of the host. He completed graduate work at the University of California, Berkeley, studying transcription elongation in the laboratory of Caroline Kane, Ph.D.. Probiotics can populate the gut with a bevy of beneficial bacteria but to be effective, those supplemental microbes need to stick around and multiply, not pass right through. The continuity of life rests on faithful inheritance of both DNA and cellular machineries responsible for decoding the genomes. By looking at the targets of these factors, Carter hopes to uncover how a relatively unexplored part of the genome might contribute to human brain development and evolution. Laurence Florens established the Systems Mass Spectrometry Center, formerly known as Proteomics, at the Stowers Institute in July 2003 with Mike Washburn, and was named Director in 2022.

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